I’ve been wanting to do this for a long time, and I finally got around to it. I set up a sample site using a Bootstrap 5.3 template. It may not be the most visually striking design, but it does what it’s supposed to do - and it works well. All it took was a bit of custom ASP/VBScript in QS to get the navigation up and running.
I’ve never really understood why Bootstrap never introduced its own CMS. Mobirise did, but it never quite made sense as a CMS. Other platforms offer Bootstrap-based templates, but a dedicated CMS built entirely around Bootstrap’s layout system—its components, forms, utilities, and helpers—could have been a genuinely strong alternative to WordPress.